Homer1 Mediates Acute Stress-Induced Cognitive Deficits in the Dorsal Hippocampus

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Homer1 mediates acute stress-induced cognitive deficits in the dorsal hippocampus.

In recent years, the glutamatergic system has been implicated in the development and treatment of psychiatric disorders. Glutamate signaling is processed by different receptors, including metabotropic glutamate receptors (mGluRs), which in turn interact with the scaffolding protein Homer1 to modulate downstream Ca(2+) signaling. Stress is a major risk factor for the incidence of psychiatric dis...

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ژورنال

عنوان ژورنال: Journal of Neuroscience

سال: 2013

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.4333-12.2013